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Center for Applied Biotechnology and Molecular Medicine

Cranio-Maxillofacial Research

Our main research interest and expertise is in dental implantology and laser medicine in oral and maxillofacial surgery. In this regard, the development and biological analysis of new and innovative treatment options and techniques for bone regeneration and reconstruction are the major part of current research activities. Beneath laser osteotomy also the influence of piezoelectric bone cutting on bone remodelling, inflammatory processes and bone resorption are thoroughly evaluated. This is to get further information in the field of basic tissue interaction mechanisms and to define the best parameters and find advantages and limitations of each technique. The final aim is to attain newly arranged and self stabilising osteotomies not only in oral and maxillofacial surgery but also in orthopaedics and other medical disciplines. Therfore, also navigation systems and robotics are tested to extend the surgical possibilities and to improve the treatment.

In a second part, we focus is on the importance of osteotomy technique, implant design and surface modification of dental implants on successful osseointegration. Among screening studies dealing with osseointegration in different animal models, also the influence of various biomaterials, fetal cells and nano-particles on the healing process are scrutinized. Thereby genomics and proteomics will help to get a further insight in new treatment possibilities and strategies in oral and maxillofacial surgery in the future.

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PD Dr. Stefan Stübinger