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Center for Applied Biotechnology and Molecular Medicine

Publications 2012

* supported by a CABMM Start-up Grant
** performed partly on the CABMM Research Platform

Tiaden N, Hilbi H
α-Hydroxyketone synthesis and sensing by Legionelly and Vibrio.
Sensors (Basel). 2012;12(3):2899-919

PubMed

Waselau M, Patrikoski M, Juntunen M, Kujala K, Kääriäinen M, Kuokkanen H, Sándor GK, Vapaavuori O, Suuronen R, Mannerström B, von Rechenberg B, Miettinen S
Effects of bioactive glass S53P4 or beta-tricalcium phosphate and bone morphogenetic protein-2 and bone morphogenetic protein-7 on osteogenic differentiation of human adipose stem cells.
J Tissue Eng. 2012;3(1):2041731412467789

PubMed

Casanova EA, Okoniewski MJ, Cinelli P
Cross-species genome wide expression analysis during pluripotent cell determination in mouse and rat preimplantation embryos.
PLoS One. 2012;7(10):e47107

PubMed

Gerber C, Meyer DC, Von Rechenberg B, Hoppeler H, Frigg R, Farshad M
Rotator cuff muscles lose responsiveness to anabolic steroids after tendon tear and musculotendinous retraction: an experimental study in sheep.
Am J Sports Med. 2012 Nov;40(11):2454-61

PubMed

*/** Tiaden AN, Breiden M, Mirsaidi A, Weber FA, Bahrenberg G, Glanz S, Cinelli P, Ehrmann M, Richards PJ
Human serine protease HTRA1 positively regulates osteogenesis of human bone marrow-derived mesenchymal stem cells and mineralization of differentiating bone-forming cells through the modulation of extracellular matrix protein.
Stem Cells. 2012 Oct;30(10):2271-82

PubMed

Kulcsár Z, Augsburger L, Reymond P, Pereira VM, Hirsch S, Mallik AS, Millar J, Wetzel SG, Wanke I, Rüfenacht DA
Flow diversion treatment: intra-aneurismal blood flow velocity and WSS reduction are parameters to predict aneurysm thrombosis.
Acta Neurochir (Wien). 2012 Oct;154(10):1827-34

PubMed

** Klawitter M, Quero L, Klasen J, Gloess AN, Klopprogge B, Hausmann O, Boos N, Wuertz K
Curcuma DMSO extracts and curcumin exhibit an anti-inflammatory and anti-catabolic effect on human intervertebral disc cells, possibly by influencing TLR2 expression and JNK activity.
J Inflamm (Lond). 2012 Aug 21;9(1):29

PubMed

Shakhova O, Zingg D, Schaefer SM, Hari L, Civenni G, Blunschi J, Claudinot S, Okoniewski M, Beermann F, Mihic-Probst D, Moch H, Wegner M, Dummer R, Barrandon Y, Cinelli P, Sommer L
Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma.
Nat Cell Biol. 2012 Aug;14(8):882-90

PubMed

** Hauser-Gerspach I, Vadaszan J, Deronjic I, Gass C, Meyer J, Dard M, Waltimo T, Stübinger S, Mauth C
Influence of gaseous ozone in peri-implantitis: bactericidal efficacy and cellular response. An in vitro study using titanium and zirconia.
Clin Oral Investig. 2012 Aug;16(4):1049-59

PubMed

** Weiler C, Schietzsch M, Kirchner T, Nerlich AG, Boos N, Wuertz K
Age-related changes in human cervical, thoracal and lumbar intervertebral disc exhibit a strong intra-individual correlation.
Eur Spine J. 2012 Aug;21 Suppl 6:S810-8

PubMed

** Klawitter M, Quero L, Klasen J, Liebscher T, Nerlich A, Boos N, Wuertz K
Triptolide exhibits anti-inflammatory, anti-catabolic as well as anabolic effects and suppresses TLR expression and MAPK activity in IL-1β treated human intervertebral disc cells.
Eur Spine J. 2012 Aug;21 Suppl 6:S850-9

PubMed

Templin C, Zweigerdt R, Schwanke K, Olmer R, Ghadri JR, Emmert MY, Müller E, Küest SM, Cohrs S, Schibli R, Kronen P, Hilbe M, Reinisch A, Strunk D, Haverich A, Hoerstrup S, Lüscher TF, Kaufmann PA, Landmesser U, Martin U
Transplantation and tracking of human-induced pluripotent stem cells in a pig model of myocardial infarction: assessment of cell survival, engraftment, and distribution by hybrid single photon emission computed tomography/computed tomography of sodium iodide symporter transgene expression.
Circulation. 2012 Jul 24;126(4):430-9

PubMed

Plecko M, Lagerpusch N, Pegel B, Andermatt D, Frigg R, Koch R, Sidler M, Kronen P, Klein K, Nuss K, Gedet P, Bürki A, Ferguson SJ, Stoeckle U, Auer JA, von Rechenberg B
The influence of different osteosynthesis configurations with locking compression plates (LCP) on stability and fracture healing after an oblique 45° angle osteotomy.
Injury. 2012 Jul;43(7):1041-51

PubMed

*/** Tiaden AN, Klawitter M, Lux V, Mirsaidi A, Bahrenberg G, Glanz S, Quero L, Liebscher T, Wuertz K, Ehrmann M, Richards PJ
Detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degeneration.
J Biol Chem. 2012 Jun 15;287(25):21335-45

PubMed

** Erener S, Mirsaidi A, Hesse M, Tiaden AN, Ellingsgaard H, Kostadinova R, Donath MY, Richards PJ, Hottiger MO
ARTD1 deletion causes increased hepatic lipid accumulation in mice fed a high-fat diet and impairs adipocyte function and differentiation.
FASEB J. 2012 Jun;26(6):2631-8

PubMed

Zumstein MA, Frey E, von Rechenberg B, Frigg R, Gerber C, Meyer DC
Device for lengthening of a musculotendinous unit by direct continuous traction in the sheep.
BMC Vet Res. 2012 May 2;8:50

PubMed

** Kelm JM, Breitbach M, Fischer G, Odermatt B, Agarkova I, Fleischmann BK, Hoerstrup SP
3D microtissue formation of undifferentiated bone marrow mesenchymal stem cells leads to elevated apoptosis.
Tissue Eng Part A. 2012 Apr;18(7-8):692-702

PubMed

** Mirsaidi A, Kleinhans KN, Rimann M, Tiaden AN, Stauber M, Rudolph KL, Richards PJ
Telomere length, telomerase activity and osteogenic differentiation are maintained in adipose-derived stromal cells from senile osteoporotic SAMP6 mice.
J Tissue Eng Regen Med. 2012 May;6(5):378-90

PubMed

von Plocki SC, Armbruster D, Klein K, Kämpf K, Zlinszky K, Hilbe M, Kronen P, Gruskin E, von Rechenberg B
Biodegradable sleeves for metal implants to prevent implant-associated infection: an experimental in vivo study in sheep.
Vet Surg. 2012 Apr;41(3):410-21

PubMed

* Guetg C, Scheifele F, Rosenthal F, Hottiger MO, Santoro R
Inheritance of silent rDNA chromatin is mediated by PARP1 via noncoding RNA.
Mol Cell. 2012 Mar 30;45(6):790-800

PubMed

Plecko M, Sievert C, Andermatt D, Frigg R, Kronen P, Klein K, Stübinger S, Nuss K, Bürki A, Ferguson S, Stoeckle U, von Rechenberg B
Osseointegration and biocompatibility of different metal implants - a comparative experimental investigation in sheep.
BMC Musculoskelet Disord. 2012 Mar 8;13:32

PubMed

** Wuertz K, Vo N, Kletsas D, Boos N
Inflammatory and catabolic signalling in intervertebral discs: the roles of NF-κB and MAP kinases.
Eur Cell Mater. 2012 Feb 16;23:103-19; discussion 119-20

PubMed