Laurent A, Porcello A, Fernandez PG, Jeannerat A, Peneveyre C, Abdel-Sayed P, Scaletta C, Hirt-Burri N, Michetti M, de Buys Roessingh A, Raffoul W, Allémann E, Jordan O, Applegate LA
Combination of Hyaluronan and Lyophilized Progenitor Cell Derivatives: Stabilization of Functional Hydrogel Products for Therapeutic Management of Tendinous Tissue Disorders
Pharmaceutics. 2021 Dec 19;13(12):2196
PubMed |
Laurent A, Abdel-Sayed P, Scaletta C, Laurent P, Laurent E, Michetti M, de Buys Roessingh A, Raffoul W, Hirt-Burri N, Applegate LA
Back to the Cradle of Cytotherapy: Integrating a Century of Clinical Research and Biotechnology-Based Manufacturing for Modern Tissue-Specific Cellular Treatments in Switzerland
Bioengineering (Basel). 2021 Dec 17;8(12):221
PubMed |
Tosoratti E, Fisch P, Taylor S, Laurent-Applegate LA, Zenobi-Wong M
3D-Printed Reinforcement Scaffolds with Targeted Biodegradation Properties for the Tissue Engineering of Articular Cartilage.
Adv Healthc Mater. 2021 Dec;10(23):e2101094
PubMed |
** Spiru B, Torres-Netto EA, Kling S, Hafezi F, Sekundo W
Hyperopic SMILE Versus FS-LASIK: A Biomechanical Comparison in Human Fellow Corneas.
J Refract Surg. 2021 Dec;37(12):810-815
PubMed |
Levinson C, Cavalli E, von Rechenberg B, Zenobi-Wong M, Darwiche SE
Combination of a Collagen Scaffold and an Adhesive Hyaluronan-Based Hydrogel for Cartilage Regeneration: A Proof of Concept in an Ovine Model
Cartilage. 2021 Dec;13(2_suppl):636S-649S
PubMed |
Flück M, Kasper S, Benn MC, Clement Frey F, von Rechenberg B, Giraud MN, Meyer DC, Wieser K, Gerber C
Transplant of Autologous Mesenchymal Stem Cells Halts Fatty Atrophy of Detached Rotator Cuff Muscle After Tendon Repair: Molecular, Microscopic, and Macroscopic Results From an Ovine Model
Am J Sports Med. 2021 Dec;49(14):3970-3980
PubMed |
Frohns A, Stojanovic M, Barisani-Asenbauer T, Kuratli J, Borel N, Inic-Kanada A
Effects of water-filtered infrared A and visible light (wIRA/VIS) radiation on heat- and stress-responsive proteins in the retina and cornea of guinea pigs.
J Photochem Photobiol B. 2021 Nov;224:112306
PubMed |
Freitag JRB, Wilkens MR, Muscher-Banse AS, Gerstner K, Schnepel N, Torgerson PR, Liesegang A
Effects of diets differing in dietary cation-anion difference and calcium concentration on calcium homeostasis in neutered male sheep
J Dairy Sci. 2021 Nov;104(11):11537-11552.
PubMed |
Jeannerat A, Peneveyre C, Armand F, Chiappe D, Hamelin R, Scaletta C, Hirt-Burri N, de Buys Roessingh A, Raffoul W, Applegate LA, Laurent A
Hypoxic Incubation Conditions for Optimized Manufacture of Tenocyte-Based Active Pharmaceutical Ingredients of Homologous Standardized Transplant Products in Tendon Regenerative Medicine.
Cells. 2021 Oct 25;10(11):2872
PubMed |
Klemmer VA, Khera N, Siegenthaler BM, Bhattacharya I, Weber FE, Ghayor C
Effect of N-Vinyl-2-Pyrrolidone (NVP), a Bromodomain-Binding Small Chemical, on Osteoblast and Osteoclast Differentiation and Its Potential Application for Bone Regeneration.
Int J Mol Sci. 2021 Oct 13;22(20):11052
PubMed |
** Vinciguerra R, Ambrósio R Jr, Elsheikh A, Hafezi F, Yong Kang DS, Kermani O, Koh S, Lu N, Padmanabhan P, Roberts CJ, Taneri S, Trattler W, Eliasy A, Jum I, Lopes B, Padmanaban V, Rosetta P, Rost A, Torres-Netto EA, Vinciguerra P
Detection of postlaser vision correction ectasia with a new combined biomechanical index.
J Cataract Refract Surg. 2021 Oct 1;47(10):1314-1318
PubMed |
Pantet O, Laurent A, Abdel-Sayed P, Hirt-Burri N, Michetti M, Raffoul W, Monod M, Applegate LA, de Buys Roessingh AS
Effective Management Of Topical Nosocomial Aspergillus Spp. Infections In Three Severly Burned Patients.
Ann Burns Fire Disasters. 2021 Sep 30;34(3):235-239
PubMed |
Chemali M, Laurent A, Scaletta C, Waselle L, Simon JP, Michetti M, Brunet JF, Flahaut M, Hirt-Burri N, Raffoul W, Applegate LA, de Buys Roessingh AS, Abdel-Sayed P
Burn Center Organization and Cellular Therapy Integration: Managing Risks and Costs
J Burn Care Res. 2021 Sep 30;42(5):911-924
PubMed |
Laurent A, Abdel-Sayed P, Hirt-Burri N, Scaletta C, Michetti M, de Buys Roessingh A, Raffoul W, Applegate LA
Evolution of Diploid Progenitor Lung Cell Applications: From Optimized Biotechnological Substrates to Potential Active Pharmaceutical Ingredients in Respiratory Tract Regenerative Medicine
Cells. 2021 Sep 24;10(10):2526
PubMed |
** Torres-Netto EA, Gabel-Obermaier C, Gabel P, Gloor B, Wiedemann P, Taylor H, Davey C, Quilter N, Seitz B
Twenty years of International Council of Ophthalmology fellowships: description of the programme and the impact on more than 1100 awardees.
Br J Ophthalmol. 2021 Sep;105(9):1318-1324
PubMed |
Beltrán Bernal LM, Canbaz F, Darwiche SE, Nuss KMR, Friedrich NF, Cattin PC, Zam A
Optical fibers for endoscopic high-power Er:YAG laserosteotomy.
J Biomed Opt. 2021 Sep;26(9):095002
PubMed |
Acevedo Rua L, Mumme M, Manferdini C, Darwiche S, Khalil A, Hilpert M, Buchner DA, Lisignoli G, Occhetta P, von Rechenberg B, Haug M, Schaefer DJ, Jakob M, Caplan A, Martin I, Barbero A, Pelttari K
Engineered nasal cartilage for the repair of osteoarthritic cartilage defects.
Sci Transl Med. 2021 Sep;13(609):eaaz4499
PubMed |
** Kling S, Torres-Netto EA, Adshahzadeh H, Espana EM, Hafezi F
Collagen V insufficiency in a mouse model for Ehlers Danlos-syndrome affects viscoelastic biomechanical properties explaining thin and brittle corneas
Sci Rep. 2021 Aug 30;11(1):17362
PubMed |
Laurent A, Scaletta C, Abdel-Sayed P, Michetti M, Flahaut M, Simon JP, Roessingh AB, Raffoul W, Hirt-Burri N, Applegate LA
Optimized Manufacture of Lyophilized Dermal Fibroblasts for Next-Generation Off-the-Shelf Progenitor Biological Bandages in Topical Post-Burn Regenerative Medicine
Biomedicines. 2021 Aug 23;9(8):1072
PubMed |
** Hafezi F, Richoz O, Torres-Netto EA, Hillen M, Hafezi N
Reply: Corneal Cross-linking at the Slit Lamp: Concern About Risk of Corneal Ulcer
J Refract Surg. 2021 Aug;37(8):572-573
PubMed |
** Hafezi F
Corneal Cross-linking for Keratoconus: Exploring the Issues Regarding Accelerated Protocols and Thin Corneas
J Ophthalmic Vis Res. 2021 Jul 29;16(3):314-316
PubMed |
** Wu D, Lim DK, Lim BXH, Wong N, Hafezi F, Manotosh R, Lim CHL
Corneal Cross-Linking: The Evolution of Treatment for Corneal Diseases
Front Pharmacol. 2021 Jul 19;12:686630
PubMed |
Khera N, Ghayor C, Pavlova E, Atanassova N, Weber FE
Exposure to the bromodomain inhibtor N-methyl pyrrolidone blocks spermatogenesis in a hormonal fashion
Toxicol Appl Pharmacol. 2021 Jul 15;423:115568
PubMed |
Klein K, Schweizer TA, Siwy K, Lechmann B, Karol A, von Rechenberg B, Achermann Y, Darwiche SE
Establishment of a localized acute implant-associated Staphylococcus aureus bone infection model in sheep
Pathog Dis. 2021 Jul 2;79(6):ftab032
PubMed |
** Torres-Netto EA, Hafezi F, Spiru B, Gilardoni F, Hafezi NL, Gomes JAP, Randleman JB, Sekundo W, Kling S
Contribution of Bowman layer to corneal biomechanics.
J Cataract Refract Surg. 2021 Jul 1;47(7):927-932
PubMed |
Jafari P, Luscher A, Siriwardena T, Michetti M, Que YA, Rahme LG, Reymond JL, Raffoul W, Van Delden C, Applegate LA, Köhler T
Antimicrobial Peptide Dendrimers and Quorum-Sensing Inhibitors in Formulating Next-Generation Anti-Infection Cell Therapy Dressings for Burns.
Molecules. 2021 Jun 24;26(13):3839
PubMed |
Lotz B, Bothe F, Deubel AK, Hesse E, Renz Y, Werner C, Schäfer S, Böck T, Groll J, von Rechenberg B, Richter W, Hagmann S
Preclinical Testing of New Hydrogel Materials for Cartilage Repair: Overcoming Fixation Issues in a Large Animal Model.
Int J Biomater. 2021 Jun 19;2021:5583815
PubMed |
Machi P, Luft A, Winklhofer S, Anagnostakou V, Kulcsár Z
Endovascular treatment of acute ischemic stroke.
J Neurosurg Sci. 2021 Jun;65(3):259-268
PubMed |
** Lopes B, Padmanabhan P, Zhang H, Abass A, Eliasy A, Bandeira F, Bao F, Bühren J, Elmassry A, Faria-Correia F, Rocha K, Rechichi M, Romano V, Torres-Netto EA, Vinciguerra R, Vinciguerra P, Elsheikh A
Clinical Validation of the Automated Characterization of Cone Size and Center in Keratoconic Corneas.
J Refract Surg. 2021 Jun;37(6):414-421
PubMed |
** Frese L, Darwiche SE, von Rechenberg B, Hoerstrup SP, Giovanoli P, Calcagni M
Thermal conditioning improves quality and speed of keratinocyte sheet production for burn wound treatment
Cytotherapy. 2021 Jun;23(6):536-547
PubMed |
** Abad JC, Martinez-Cadavid L, Ocampo-Patiño A, Torres-Netto EA, Ambrosio R
Severe long-term progressive corneal remodeling after bilateral simultaneous prophylactic crosslinking and topography-guided surface ablation with mitomycin
Am J Ophthalmol Case Rep. 2021 May 24;23:101120
PubMed |
** Abrishamchi R, Abdshahzadeh H, Hillen M, Hafezi N, Torres-Netto EA, Aslanides IM, Chen S, Randleman JB, Hafezi F
High-Fluence Accelerated Epithelium-Off Corneal Cross-Linking Protocol Provides Dresden Protocol-Like Corneal Strengthening
Transl Vis Sci Technol. 2021 Apr 29;10(5):10
PubMed |
Laurent A, Abdel-Sayed P, Grognuz A, Scaletta C, Hirt-Burri N, Michetti M, de Buys Roessingh AS, Raffoul W, Kronen P, Nuss K, von Rechenberg B, Applegate LA, Darwiche SE
Industrial Development of Standardized Fetal Progenotor Cell Therapy for Tendon Regenerative Medicine: Preliminary Safety on Xenogeneic Transplantation
Biomedicines. 2021 Apr 3;9(4):380
PubMed |
Schwarzenberg P, Klein K, Ferguson SJ, von Rechenberg B, Darwiche S, Daley HL
Virtual mechanical tests out-perform morphometric measures for assessment of mechanical stability of fracture healing in vivo
J Orthop Res. 2021 Apr;39(4):727-738
PubMed |
** Hafezi F, Kling S, Gilardoni F, Hafezi N, Hillen M, Abrishamchi R, Gomes JAP, Mazzotta C, Randleman JB, Torres-Netto EA
Individualized Corneal Cross-linking With Riboflavin and UV-A in Ultrathin Corneas: The Sub400 Protocol.
Am J Ophthalmol. 2021 Apr;224:133-142
PubMed |
Schwarzenberg P, Ren T, Klein K, von Rechenberg B, Darwiche S, Dailey HL
Domain-independent simulation of physiologically relevant callus shape in mechanoregulated models of fracture healing
J Biomech. 2021 Mar 30;118:110300
PubMed |
Al-Dourobi K, Laurent A, Deghayli L, Flahaut M, Adel-Sayed P, Scaletta C, Michetti M, Waselle L, Simon JP, Ezzi OE, Raffoul W, Applegate LA, Hirt-Burri N, Roessingh ASB
Retrospective Evaluation of Progenitor Biological Bandage Use: A Complementary and Safe Therapeutic Management Option for Prevention of Hypertrophic Scarring in Pediatric Burn Care
Pharmaceuticals (Basel). 2021 Feb 28;14(3):201
PubMed |
** Laurent A, Abdel-Sayed P, Ducrot A, Hirt-Burri N, Scaletta C, Jaccoud S, Nuss K, Roessingh ASB, Raffoul W, Pioletti D, Rechenberg BV, Applegate LA, Darwiche S
Development of Standardized Fetal Progenitor Cell Therapy for Cartilage Regenerative Medicine: Industrial Transposition and Preliminary Safety in Xenogeneic Transplantation
Biomolecules. 2021 Feb 9;11(2):250
PubMed |
** Abdshahzadeh H, Abrishamchi R, Torres-Netto EA, Kling S, Hafezi NL, Hillen M, Hafezi F
Impact of hypothermia on the biomechanical effect of epithelium-off corneal cross-linking
Eye Vis (Lond). 2021 Feb 9;8(1):4
PubMed |
Paunović N, Bao Y, Coulter FB, Masania K, Geks AK, Klein K, Rafsanjani A, Cadalbert J, Kronen PW, Kleger N, Karol A, Luo Z, Rüber F, Brambilla D, von Rechenberg B, Franzen D, Studart AR, Leroux JC
Digital light 3D printing of customized bioresorbable airway stents with elastomeric properties
Sci Adv. 2021 Feb 3;7(6):eabe9499
PubMed |
** Hafezi F, Richoz O, Torres-Netto EA, Hillen M, Hafezi NL
Corneal Cross-linking at the Slit Lamp
J Refract Surg. 2021 Feb 1;37(2):78-82
PubMed |
** Awwad ST, Chacra LM, Helwe C, Dhaini AR, Telvizian T, Torbey J, Abdul Fattah M, Torres-Netto EA, Hafezi F, Shetty R
Mitomycin C Application After Corneal Cross-linking for Keratoconus Increases Stromal Haze
J Refract Surg. 2021 Feb 1;37(2):83-90
PubMed |
** Hafezi F, Torres-Netto EA, Hillen MJP
Re: Prajna et al.: Cross-Linking-Assisted Infection Reduction: a randomized clinical trial evaluating the effect of adjuvant cross-linking on outcomes in fungal keratitis (Ophthalmology. 2020;127:159-166).
Ophthalmology. 2021 Jan;128(1):e6
PubMed |
Laurent A, Scaletta C, Michetti M, Hirt-Burri N, Flahaut M, Raffoul W, de Buys Roessingh AS, Applegate LA
Progenitor Biological Bandages: An Authentic Swiss Tool for Safe Therapeutic Management of Burns, Ulcers, and Donor Site Grafts.
Methods Mol Biol. 2021;2286:49-65
PubMed |
Laurent A, Scaletta C, Michetti M, Hirt-Burri N, de Buys Roessingh AS, Raffoul W, Applegate LA
GMP Tiered Cell Banking of Non-enzymatically Isolated Dermal Progenitor Fibroblasts for Allogenic Regenerative Medicine.
Methods Mol Biol. 2021;2286:25-48
PubMed |
Laurent A, Scaletta C, Hirt-Burri N, Raffoul W, de Buys Roessingh AS, Applegate LA
Swiss Fetal Transplantation Program and Non-enzymatically Isolated Primary Progenitor Cell Types for Regenerative Medicine.
Methods Mol Biol. 2021;2286:1-24
PubMed |
** Knyazer B, Hillen M, Hafezi F
Corneal Cross-linking for Infectious Keratitis at the Slit Lamp in Wheelchair Users.
J Refract Surg Case Rep. 2021;1(3):e36-e39
Healio |
** Hafezi F, Torres-Netto EA, Randleman JB, Hafezi NL, Mazzotta C, Ambrósio Jr R, Kollros L
Corneal Cross-linking for Keratoglobus Using Individualized Fluence.
J Refract Surg Case Rep. 2021;1(1):e10-e14
Healio |
* Gantenbein B, May RD, Bermudez-Lekerika P, Oswald KAC, Benneker LM, Albers CE
EGR2, IGF1 and IL6 Expression Are Elevated in the Intervertebral Disc of Patients Suffering from Diffuse Idiopathic Skeletal Hyperostosis (DISH) Compared to Degenerative or Trauma Discs
Appl Sci. 2021;11(9):4072
MDPI |