2012

Tiaden AN, Breiden M, Mirsaidi A, Weber FA, Bahrenberg G, Glanz S, Cinelli P, Ehrmann M, Richards PJ
Human Serine Protease HTRA1 Positively Regulates Osteogenesis of Human Bone Marrow-Derived Mesenchymal Stem Cells and Mineralization of Differentiating Bone- Forming Cells through the Modulation of Extracellular Matrix Protein.
Stem Cells 2012;30:2271-2282.

PubMed Group Richards

Klawitter M, Quero L, Klasen J, Gloess A, Klopprogge B, Hausmann O, Boos N, Wuertz
Curcuma DMSO extracts and curcumin exhibit an anti-inflammatory and anti-catabolic effect on human intervertebral disc cells, possibly by influencing TLR2 expression and JNK activity.
J Inflamm (Lond). 2012 Aug 21;9(1):29.

PubMed Group Würtz

Hauser-Gerspach I, Vadaszan J, Deronjic I, Gass C, Meyer J, Dard M, Waltimo T, Stübinger S, Mauth C
Influence of gaseous ozone in peri-implantitis: bactericidal efficacy and cellular response. An in vitro study using titanium and zirconia.
Clin Oral Investig. 2012 Aug;16(4):1049-59.

PubMed Group Stübinger

Weiler C, Schietzsch M, Kirchner T, Nerlich AG, Boos N, Wuertz K
Age-related changes in human cervical, thoracal and lumbar intervertebral disc exhibit a strong intra-individual correlation.
Eur Spine J. 2012 Aug;21 Suppl 6:810-8.

PubMed Group Würtz

Klawitter M, Quero L, Klasen J, Liebscher T, Nerlich A, Boos N, Wuertz K
Triptolide exhibits anti-inflammatory, anti-catabolic as well as anabolic effects and suppresses TLR expression and MAPK activity in IL-1β treated human intervertebral disc cells.
Eur Spine J. 2012 Aug;21 Suppl 6:850-9.

PubMed Group Würtz

Tiaden AN, Klawitter M, Lux V, Mirsaidi A, Bahrenberg G, Glanz S, Quero L, Liebscher T, Wuertz K, Ehrmann M, Richards PJ
A detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degeneration.
J. Biol. Chem. 2012;287(25):21335-45.

PubMed Group Richards Group Würtz

Erener S, Mirsaidi A, Hesse M, Tiaden AN, Ellingsgaard H, Kostadinova R, Donath MY, Richards PJ, Hottiger MO
ARTD1 deletion causes increased hepatic lipid accumulation in mice fed a high-fat diet and impairs adipocyte function and differentiation.
FASEB J. 2012;26(6):2631-8.

PubMed Group Richards Group Hottiger

Kelm JM, Breitbach M, Fischer G, Odermatt B, Agarkova I, Fleischmann BK, Hoerstrup S
3D Microtissue Formation of Undifferentiated Bone Marrow Mesenchymal Stem Cells Leads to Elevated Apoptosis.
Tissue Eng Part A. 2012 Apr. 18(7-8):692-702.

PubMed

Mirsaidi A, Kleinhans KN, Rimann M, Tiaden AN, Stauber M, Rudolph KL, Richards PJ
Telomere length, telomerase activity and osteogenic differentiation are maintained in adipose-derived stromal cells from senile osteoporotic SAMP6 mice.
J Tissue Eng Reg Med; 2012;6(5):378-90.

PubMed Group Richards

Plecko M, Sievert C, Andermatt D, Frigg R, Kronen P, Klein K, Stübinger S, Nuss K, Bürki A, Ferguson S, Stoeckle U, von Rechenberg B
Osseointegration and biocompatibility of different metal implants - a comparative experimental investigation in sheep.
BMC Musculoskeletal Disord. 2012 Mar 8;13:32.

PubMed Group Stübinger

Wuertz K, Vo N, Kletsas D, Boos N
Inflammatory and catabolic signalling in intervertebral discs: the roles of NF-κB and MAP kinases.
Eur Cell Mater. 2012;23:103-19

PubMed Group Würtz